Nano, Bio, Info, Cogno, Synthetic bio, NBICS

Where I post what I find interesting in regards to NBICS and social implications

Archive for October, 2006

Cognitive Enhancement: Methods, Ethics, Regulatory Challenges

Posted by wolbring on October 22, 2006

Nick Bostrom
with Anders Sandberg
October 18, 2006

Cognitive enhancement comes in many diverse forms. In this paper, we survey the current state of the art in cognitive enhancement methods and consider their prospects for the near-term future. We then review some of ethical issues arising from these technologies. We conclude with a discussion of the challenges for public policy and regulation created by present and anticipated methods for cognitive enhancement.

Link to Source

Posted in Cogno, Neuro | No Comments »

Biology via design, and print via 3-D

Posted by wolbring on October 21, 2006

Biology via design, and print via 3-D
By Conrad de Aenlle International Herald Tribune

Published: October 20, 2006
The marvels of the information age exist mainly in two dimensions on a computer disk or monitor. In the post-information age, they are expected to be more tangible and substantial, occupying the same three-dimensional space we do.

One of the most intriguing developments anticipated by Marina Gorbis, executive director of the Institute of the Future, is “intentional biology,” or genetic, pharmaceutical or mechanical biological alteration. “We’re going to be able to design and manipulate our bodies more and more and hack into them in various ways,” she predicted.

Three pioneers in this field - Synthetic Genomics, founded by Craig Venter, a leading figure in mapping the human genome; Codon Devices; and Amyris Biotechnologies - are hacking into lower forms of life, for now, including organisms invented in their labs.

Two companies Gorbis mentioned that work on the human nervous system were Cyberkinetics, which makes neural stimulation devices, and the drug maker Memory Pharmaceuticals.

Another nascent development expected to flourish in coming decades is a three-dimensional printer that would use nanotechnology to make physical objects by dispersing molecules according to programmed patterns, much as a conventional printer sprays ink to form words and images on a page.

“You put in a formula and design for something, and the printer will etch, layer by layer, the actual three-dimensional object,” Gorbis said. She emphasized that the results would not be holographic images or other facsimiles, but actual objects, including functional electronic equipment.

She expects 3-D printers to be a fact of commercial life “definitely in the next 20 to 30 years,” but some companies, notably Z Corp. and Stratasys, are getting a head start. They make prototypical printers used in industrial design.

The big promise of 3-D printers is that they will usher in a new era of home-based manufacturing and unprecedented choice, Gorbis said. She foresees an intermediate stage in which makers of, say, cellphones invite customers to a store to create the handset of their choice on the spot. After that, she said, they may become fairly ordinary pieces of household equipment.

“This changes the way we think about materials,” she said. “You just get the chemical package and assemble it. This allows us to create light products that are highly flexible and personal.”

The marvels of the information age exist mainly in two dimensions on a computer disk or monitor. In the post-information age, they are expected to be more tangible and substantial, occupying the same three-dimensional space we do.

One of the most intriguing developments anticipated by Marina Gorbis, executive director of the Institute of the Future, is “intentional biology,” or genetic, pharmaceutical or mechanical biological alteration. “We’re going to be able to design and manipulate our bodies more and more and hack into them in various ways,” she predicted.

Three pioneers in this field - Synthetic Genomics, founded by Craig Venter, a leading figure in mapping the human genome; Codon Devices; and Amyris Biotechnologies - are hacking into lower forms of life, for now, including organisms invented in their labs.

Two companies Gorbis mentioned that work on the human nervous system were Cyberkinetics, which makes neural stimulation devices, and the drug maker Memory Pharmaceuticals.

Read More

Posted in NBICS, Nano scale technologies/sciences, Synthetic Biology, nano | No Comments »

Communication and risk assessment: keys to unleashing nano-potential

Posted by wolbring on October 21, 2006

[Date: 2006-10-20]
Link to Source
‘Science and politics do not always dance together easily,’ said Dutch MEP Dorette Corbey, speaking on the first day of the European Forum on Nanosciences in Brussels on 19 October.

When the science in question has evoked some controversy, politicians and scientists can be even less in step. But both were present at the forum, and dancing to the same tune as they examined the potential of nanoscience and nanotechnology, raising awareness of this relatively young field, and risk and risk perception.

Both scientists and politicians are dependent upon one another, and it therefore makes sense for them to work together and agree upon a common approach to nanoscience. Scientists, and particularly those in the public sector, require funding, as well as appropriate regulations, if any are put in place; governments are responsible for ensuring that their citizens are not exposed to any harm, and that opportunities to climb up the competitiveness ladder are not missed.

If the full potential of nanoscience is to be exploited however, public concerns must be taken into account, whether or not they are believed to be justified. If Europe does not address problems early on, they will come back later with more force, said Science and Research Commissioner Janez Potocnik. ‘We must patiently explain [...]. Hiding things will bring even bigger problems in the future,’ he added.

This view contrasts somewhat with that of Giovanni Carrada, a science journalist. One of the lessons learned from the Genetically Modified Organisms (GMO) affair was that more technical information is not the answer. ‘You can never turn the general public into experts,’ he told the conference.

Mr Carrada listed other lessons learned from GMOs as: the source rather than the content of information will either win or lose the public’s trust; uncertainties must be acknowledged; citizens should be involved upstream; technologies should not be regarded as machines.

A number of speakers agreed on the importance of involving the general public in nanoscience from the beginning. ‘Initial perceptions are very difficult to change. They frame the issue for a very long time,’ said Mr Carrada. What makes this difficult with nanoscience, as highlighted from Donald Bruce of the Church of Scotland, is that the concept is still quite vague, and is therefore not attracting much interest from society. Indeed, a Eurobarometer on nanotechnology showed a very low awareness of the subject. Instead, Mr Bruce suggested communication strategies focusing on the many areas where nanoscience is developing - nanomedicine and nanotechnology for the environment, for example.

While there are still risks to be assessed in these two areas, the potential for improving quality of life is enormous. In healthcare for example, nanoscience can improve diagnosis, the monitoring of conditions, and treatment with the aid of nanosized tools.

Ruth Duncan is a Professor of Cell Biology and Drug Delivery at the Welsh School of Pharmacy, Cardiff University, UK, and Director of the Centre for Polymer Therapeutics. She gave an introduction to what could be achieved in nanomedicine, but then referred to some of the challenges that must be addressed first. ‘We must give realistic timelines,’ she said.

Of course the new technology must be safe. In addition, researchers are under immense pressure to find effective inexpensive materials. When new materials or technologies are developed, this knowledge must be translated into a product, and exploited on the marketplace. Professor Duncan referred to a number of products that have been developed in Europe but exploited in the US. ‘We don’t want to be buying technologies back later through licensing agreements. This is far too expensive,’ she said. Part of the solution may be helping scientists to understand the needs of the manufacturing sector, she suggested.

Fragmented research efforts are also standing in the way of nanomedicine, according to Professor Duncan. She appealed for pan-European efforts and pan-European standards. More integration is also needed between disciplines, she said, calling for more inter-disciplinary conferences bringing scientists from traditionally separate disciplines together, and more degree courses on, for example, nanomedicine.

The interdisciplinary approach is also important at European level, she stressed. ‘My concern was that in earlier framework programmes, nano was in one box and health in another. We need an integrated approach,’ said Professor Duncan. She is confident that the Seventh Framework Programme (FP7) provides this integrated approach.

Finally, Professor Duncan returned to the subject of communication. Scientists need to engage with the public, and interact with politicians. She lamented the fact that few MEPs attended the Forum on Nanosciences. Their absence was partly due to their heavy schedules, but partly to nano-experts not ’speaking the right language’, she said.

As debates in the media pick up speed over the risk of nanoscience on the one hand, and its potential on the other, politicians are however taking an interest. On 28 November MEPs adopted an own initiative report welcoming a Commission action plan on a safe, integrated and responsible strategy for nanosciences and nanotechnologies for the period 2005 to 2009. The report by Czech MEP Miloslav Ransdorf stresses the need to increase public investment in research as world-class infrastructure is needed if the EU is to remain competitive in nanoscience.

The report also called upon the EU to clarify the legal and business environment for new nanotechnologies, and to create a nanoscience patent monitoring system governed by the European Patent Office.

For further information on the European Forum on Nanosciences, please visit:
http://www.cost.esf.org/index.php?id=875

For further information on nanoscience and nanotechnology, please visit:
http://cordis.europa.eu/nanotechnology/

Posted in Nano scale technologies/sciences, nano | No Comments »

Hip chip uses nanotechnology to monitor healing

Posted by wolbring on October 21, 2006

(Nanowerk News) It is as small as the tip of a pen, but a microsensor created by University of Alberta engineers may soon make a huge difference in the lives of people recovering from hip replacement surgery.
The U of A research team has invented a wireless microsensor to monitor the bone healing process after surgery. Using nanotechnology, the researchers built a tiny device that measures the degree to which bone attaches itself to a surgical implant - a process called osseointegration - and lets doctors know when the joint needs to be replaced.
“The ability to monitor and quantify this healing process is critical to orthopedic surgeons in determining a patient’s rehabilitation progress,” said Dr. Walied Moussa, a professor in the Department of Mechanical Engineering, who has a lab in the National Research Council’s National Institute for Nanotechnology, based at the U of A. “Until now, there has been no quantitative method for assessing osseointegration.”
“This microsensor not only reduces post-operation recovery time, it will also help reduce the wait time for patients needing artificial joint implants,” he said.
The sensor will be permanently implanted with the joint and is powered kinetically - it uses the natural movement of the patient’s body as its power source. It stays dormant until a doctor asks it to start transmitting data.
Careful monitoring of how patients are healing will help them recover as quickly as possible and resume normal activities with less chance of stressing the fracture during recovery and rehabilitation. It also allows the surgeon to more accurately decide when it is safe to send patients home from the hospital with their new implants.
The device will also cut down the need for X-rays to monitor bone functionality, reducing costs and exposure to radiation. And the sensor can detect and identify bone loss before it’s even visible on a radiograph.
This research can also be applied to artificial knees, hip replacement and other joint therapy.
Earlier this year, TEC Edmonton, a joint initiative of the U of A and Edmonton Economic Development Corp., filed a provisional U.S. patent application for the work.
Moussa collaborated on this project with Dr. Edmond Lou, a research associate in the Rehabilitation and Technology Department of Glenrose Hospital in Edmonton and an adjunct professor in the Department of Electrical and Computer Engineering, and Dr. John Cinats, section head of orthopedics for Capital Health and associate clinical professor at the University of Alberta Hospital.
Source: University of Alberta

Link to Source of the above article

and here

Posted in Health, NBICS, Nano scale technologies/sciences, nano | No Comments »

Green chimney could save the planet

Posted by wolbring on October 21, 2006

A new power plant chimney that converts greenhouse gases into helpful substances could have a huge impact on global warming.
By David Whitford, FSB Magazine
October 20 2006: 9:10 AM EDT
Read more here

Posted in Renewable Energy/Energy in general | No Comments »

Nano-forestry

Posted by wolbring on October 20, 2006

I published a column on Nanoforestry recently
and since than other news appeared e.g. Nanocoating woodfibers results in smart paper. In the column I also dealt with the link between nano-forestry and biofuel and with the link between synthetic biology and biofuel and right after I published my nanoforestry column I saw the news item Amyris Biotechnologies Synthetic Biology Pioneer Expands Into Bioenergy Field which I mentioned in the blog here a few days ago. To be on top of things it seems one has to have ones sensors in the advances of many different sciences and technologies and be aware of the numerous applications all of these sciences and technologies go for. ..

Posted in NBICS, Nano scale technologies/sciences, Renewable Energy/Energy in general, Synthetic Biology, nano | 2 Comments »

Confront nanotech health risks now, experts say

Posted by wolbring on October 20, 2006

By Martin LaMonica, CNET News.com
Published on ZDNet News: October 18, 2006, 12:30 PM PT
CAMBRIDGE, Mass.–Environmental and health risks stemming from nanomaterials are real and need to be addressed head on by both industry and regulatory bodies, experts said this week at a conference.

Lux Research hosted two talks Tuesday on environmental and health safety issues related to nanotechnology here at its Lux Executive Summit, which brings together business people and investors.

Speakers did not address specific hazards that could stem from nanomaterials. Rather, they recognized that there are potential risks–some involving public perceptions–and urged business people to address them early in product development, rather than as an afterthought.

Nanotechnology is the science of working with materials at the nanoscale. A nanometer is a billionth of a meter. A human hair is about 80,000 nanometers wide.

Nanomaterials can be used in a broad range of products, from solar panels to golf balls to medicines. Lux Research earlier this year published a study that found that 148 of the world’s largest 1,331 companies have nanotechnology projects under way, with that number expected to double by 2008 and corporate R&D spending to balloon to $12 billion by then.

But even as these nanomaterials become used in commercial products, there is still not a great deal of understanding of the environmental and health safety risks, said Michael Holman, a Lux Research analyst who specializes in the area.

“We don’t know enough,” Holman said. “There is a lot of confusion that isn’t going to be resolved quickly or easily.”

Holman cited the example of fullerenes, a carbon-based molecule that is used in products such as eye cream. One test, meant to measure the impact of disposed fullerenes, found that the substance damaged the brains of largemouth bass.

Later, however, that result was disputed with some researchers arguing that fullerenes could even have a beneficial effect on those fish, he explained.

More data needed
Because of a lack of reliable data on safety issues, a panel of experts said that businesses should test for toxicity at every stage of product development. In addition, they urged companies developing new materials to work closely with federal regulatory bodies and academics.

“Environmental and health safety issues are not only part of the business cases for start-up companies, it’s fundamental to the business,” said Mark Mansour, a partner at law firm Foley & Lardner.

“I’ve seen companies go through an incredible amount of research and development and investment without consulting regulators. And then you have a business plan that doesn’t work,” he said.

Regulatory bodies in the U.S. are looking to fund further research on the health safety and environmental effects from nanomaterials. But right now there aren’t any laws or standards in place and efforts to establish them could take years.

A Nanotechnology Environmental and Health Implications Working Group, which includes several government agencies, is now working on a paper outlining research priorities.

One of the first tasks of this group is to define what should be considered nanomaterial, said Norris Alderson, the chairman of that working group and the associate commissioner for science at the U.S. Food and Drug Administration.

Continued: Self-regulation in absence of guidelines…
Read more

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ICON Releases Review of Nanotechnology Practices - Phase 1 Report

Posted by wolbring on October 20, 2006

here
more from International Council on Nanotechnology ICON here

Posted in Nano scale technologies/sciences, nano | No Comments »

Nano-rice

Posted by wolbring on October 20, 2006

Posted in Nano scale technologies/sciences, nano | No Comments »

NanoSoc: Nanotechnologies for tomorrow’s society

Posted by wolbring on October 18, 2006

Posted in Nano scale technologies/sciences, nano | No Comments »

Nextfest

Posted by wolbring on October 18, 2006

Posted in Uncategorized | No Comments »

Brainball: Winning by Relaxing

Posted by wolbring on October 18, 2006

Brainball is a game where you compete in relaxation. The players’ brainwaves control a ball on a table, and the more relaxed scores a goal over the opponent.

Brainball is a game that goes against the conventional competitive concept, and also reinvents the relationship between man and machine. Instead of activity and adrenalin, it is passivity and calmness that mark the truly successful Brainball player. Brainball is unique amongst machines since it is not controlled by the player’s rational and strategic thoughts and decisions. On the contrary, the participants are dependent on the body’s own intuitive reactions to the game machine.

At first glance, Brainball seems similar to a traditional two player game - two people challenge one and other and take their respective positions at each end of a table that is laid out with two goals and a little ball. The rest of the game’s equipment is more special. Both players wear a strap around their forehead that contains electrodes and is wired up to a biosensor system. This system, that is used to measure the body’s biological signals, is tightly fastened to the frontal lobes and registers the electrical activity in the brain - so called EEG (electro­encephalo­gram). The players brain activity is graphed in a diagram on a computer screen so that the public can easily follow the players mental processes during the match.

The brain waves that move the ball forward, increasing the chance of victory, are called alpha and theta waves. They are generated in the brain when one is calm and relaxed. A considerably stressed player will therefore lose. The matches outcome is rarely obvious since the transition between calm and stress, and vice versa, can occur quickly. Often, the ball will roll backwards and forwards for a few minutes before the game is concluded. In this way, Brainball is an exciting and social game where the audience can follow the match by watching the ball on the table, the graph on the screens and the more or less relaxed expressions of the players.

Link to Soure

see here

Posted in Uncategorized | No Comments »

TV Watching Tied To Autism, Study Says

Posted by wolbring on October 17, 2006

A news release from Cornell reported that the autism rate was 1 in 2,500 children 30 years ago, but has increased to as high as 1 in 166 as TV viewing has increased.
Link to Source

My comment: Hmmm

Posted in Uncategorized | No Comments »

From the Labs: Information Technology

Posted by wolbring on October 17, 2006

By Kate Greene
Ultrahigh-Resolution Signal Analysis
An obscure algorithm could lead to more precise radar and a better understanding of human hearing

Source: “Sparse Time-Frequency Representations”
Timothy J. Gardner et al.
Proceedings of the National Academy of Sciences 103(16): 6094-6099
Next steps: The researchers plan to apply their understanding of re­assigned time-frequency representation in an investigation of human hearing. By testing their algorithms against artificial neural networks that represent auditory nerves, they will try to create better neurological models of the way the brain makes sense of sound.
Link to Source

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Printing Fuel Cells

Posted by wolbring on October 17, 2006

Tuesday, October 17, 2006
A technique based on an inexpensive process used to print electronic circuit boards has been developed for constructing complex three-dimensional devices, such as a micro-reformer for fuel cells. The new method could be a versatile way to more cheaply and easily create microscale devices, making it practical to fabricate fuel cells for recharging two-way radios. It could also help make some types of chemical manufacturing safer and more efficient, and produce wireless-tire air-pressure sensors inexpensive enough to be standard issue in new cars.
Read More

Posted in Renewable Energy/Energy in general | No Comments »

Graphic visualization of trends

Posted by wolbring on October 16, 2006

Posted in Tools | 1 Comment »

Nanosheets That Mimic Protein Formation Made By Researchers

Posted by wolbring on October 16, 2006

How to direct and control the self-assembly of nanoparticles is a fundamental question in nanotechnology.

University of Michigan researchers have discovered a way to make nanocrystals in a fluid assemble into free-floating sheets the same way some protein structures form in living organisms.

“This establishes an important connection between two basic building blocks in biology and nanotechnology, that is, proteins and nanoparticles, and this is very exciting for assembling materials from the bottom up for a whole slew of applications ranging from drug delivery to energy,” said Sharon Glotzer, professor of chemical engineering and materials science and engineering.

Read more

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Amyris Biotechnologies Synthetic Biology Pioneer Expands Into Bioenergy Field

Posted by wolbring on October 16, 2006

Some excerpts from press release
EMERYVILLE, Calif., October 12, 2006 /PRNewswire/ — Amyris Biotechnologies, Inc., a privately-held company applying advances in synthetic biology to produce high-value pharmaceuticals, fine chemicals and biofuels, today announced that the company has raised $20 million in a first round of venture funding.

Mr. Melo stated, “I am excited about this opportunity to join a company that is using cutting-edge tools in chemistry and biology to develop solutions for major world problems, and look forward to guiding Amyris’ expansion into new areas, including polymers, specialty chemicals and nutraceuticals, in addition to biofuels.”

“The completion of this financing validates the strength of Amyris’ core technology and signals an important step in the company’s growth. These new resources will enable the company to expand its capabilities to address major global health and energy challenges, thereby helping to fulfill the promise of synthetic biology,” stated Jay D. Keasling, Ph.D., an Amyris founder, head of the company’s Scientific Advisory Board, and University of California, Berkeley, professor of chemical engineering and bioengineering. “In addition to its ongoing focus on creating a low-cost malaria drug, Amyris will add a new program aimed at renewably producing second-generation, high-performance biofuels with increased cost-effectiveness.”

Amyris Biotechnologies uses synthetic biology techniques to create new metabolic pathways in industrial microbes, turning them into living chemical factories for the efficient production of novel or rare chemicals. Amyris’ primary project to date has focused on the use of synthetic biology to address supply and cost constraints limiting the use of the life-saving anti-malarial drug, artemisinin.
Read the complete one

see also here
Amyris webpage

Posted in Synthetic Biology | No Comments »

Neurotechnology Industry Organization Launched to Advance Treatments for Brain and Nervous System Illnesses

Posted by wolbring on October 15, 2006

Oct 13 2006, 8:31 AM EST

(BIOWIRE)– More than 20 leading pharmaceutical, medical device, and diagnostic companies, along with major academic brain research centers and patient advocacy groups, have joined together to form a new trade association called the Neurotechnology Industry Organization (NIO). Based in San Francisco, California, NIO is a non-profit group created to accelerate the development of treatments and cures for brain and nervous system diseases.

The $110 billion neurotechnology industry includes pharmaceuticals, biologics, cell-based therapeutics and medical devices, as well as diagnostic and surgical equipment for critical unmet needs including: Alzheimer’s, addiction, anxiety, depression, epilepsy, hearing loss, insomnia, multiple sclerosis, obesity, pain, Parkinson’s, schizophrenia, stroke and other brain-related illnesses.

“Despite the clear need and significant market opportunity, neurotechnology companies face a host of issues that stifle innovation, growth and rapid delivery of effective therapies. NIO will provide a collective voice for commercial neuroscience organizations to address these issues,” said Zack Lynch, Founder and Executive Director of the newly formed Neurotechnology Industry Organization. “We will kick off our first year with a global awareness campaign highlighting the industry’s progress and a public policy tour for members to interact with government officials.”

Over 1.5 billion people worldwide and nearly 100 million Americans suffer from a brain or nervous system illness. In addition to untold human suffering, the annual economic burden has reached over $1 trillion worldwide with $300 billion a year in the U.S alone. This burden is accelerating as the population ages and population increases. These factors are creating unprecedented demand for treatments that delay, prevent and cure chronic neurological and psychiatric diseases.

The 500 companies involved in commercial neuroscience face fundamentally different investment requirements, research and development challenges, and regulatory milestones than other life science and healthcare companies. NIO was created to help governments, patients, and the public understand the unique needs of the neurotech industry.

“We are delighted to be a founding member of NIO,” said J. Donald deBethizy, Ph.D., President and Chief Executive Officer of Targacept, Inc. “We are pleased that this advocacy group has been formed to address the important issues of our industry.”

Founding member organizations span a broad spectrum of drug, device and diagnostic companies from across the world unified by common interests. They include: Acumen Pharmaceuticals (South San Francisco, CA), Amarin Corporation (London, England), Brain Resource Company (Sydney, Australia), Ceregene (San Diego, CA), Cyberkinetics Neurotechnology Systems Inc. (Boston, MA), NeuroPace (Mountain View, CA), NeuroNova AB (Stockholm, Sweden), Sound Pharmaceuticals (Seattle, WA), Targacept, Inc. (Winston-Salem, NC), and United Therapeutics (Silver Spring, MD); neuroscience research centers including: Allen Institute for Brain Science (Seattle, WA), Blanchette Rockefeller Neurosciences Institute (Morgantown, WV), McGovern Institute for Brain Research at MIT (Cambridge, MA), and the MIND Institute (Albuquerque, NM); patient advocacy groups and research foundations including: Alzheimer’s Drug Discovery Foundation (New York, NY), Epilepsy Therapy Development Project (Reston, VA) and Neurotech Network (Tampa, FL); venture capital firms NeuroVentures (Charlottesville, VA) and Technology Partners (Palo Alto, CA); and strategic partner Preston Gates Ellis & Rouvelas Meeds LLP (Washington, DC).

About the Neurotechnology Industry Organization

The Neurotechnology Industry Organization (NIO) is a non-profit trade association that represents a broad spectrum of companies involved in neurotechnology (drugs, devices and diagnostics), neuroscience research centers and brain disease advocacy groups across the United States and the world. NIO’s mission is to accelerate cures for brain and nervous system diseases by promoting the neurotechnology industry’s progress, advocating the industry’s position to government officials, and providing business development services to its members. For more information on the Neurotechnology Industry Organization, please visit www.neurotechindustry.org

About the Neurotechnology Industry Organization

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A Boost For Solar Cells With Photon Fusion

Posted by wolbring on October 14, 2006

October 13, 2006

An innovative process that converts low-energy longwave photons (light particles) into higher-energy shortwave photons has been developed by a team of researchers at the Max Planck Institute for Polymer Research in Mainz and at the Sony Materials Science Laboratory in Stuttgart. With the skillful combination of two light-active substances, the scientists have, for the first time, manipulated normal light, such as sunlight, to combine the energy in photons with particular wavelengths (Physical Review Letters, October 4, 2006). This has previously only been achieved with a similar process using high-energy density laser light. The successful outcome of this process could lay the foundation for a new generation of more efficient solar cells.
Read more

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