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Bioactive glass nanofibers as a next-generation biomaterial

In Uncategorized on September 11, 2006 at 9:12 am

11. Sept. (Nanowerk Spotlight) Bioactive glass is currently regarded as the most biocompatible material in the bone regeneration field because of its bioactivity, osteoconductivity (a scaffold’s ability to support cell attachment and subsequent bone matrix deposition and formation) and even osteoinductivity (a scaffold that encourages osteogenic precursor cells to differentiate into mature bone-forming cells). However, the formulation of bioactive glass has been limited to bulk, crushed powders and micronscale fibers. Now, researchers in South Korea and the UK have for the first time fabricated bioactive glass in nanofibrous form. This material, which shows excellent bioactivity, is likely to open the door to the development of new nano-structured bone regeneration materials for regenerative medicine and tissue engineering.
Materials for biomedical applications have been exploited to augment and regenerate human tissues that have been subjected to damage and diseases. Over the last decade the demands on synthetic biomaterials have increased significantly and considerable effort has been devoted to the area of biomaterials and tissue engineering.
Specifically for hard-tissue applications, such as the regeneration and repair of bones and teeth, several bioactive or bioinert materials have been used clinically. Silica-based bioglasses constitute the essential part of such bioactive materials, having already been utilized in numerous orthopedic and dental applications.
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