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New molecular switch for genes

In Uncategorized on July 31, 2007 at 1:03 pm

Researchers have created a molecular switch that can reversibly turn any mammalian gene on or off and control its level of expression. The results, published this week in Cell, provide a new level of precision in studying genes involved in biological processes and diseases, the authors say.
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Copyright © 2007 Cell Press. All rights reserved.
Cell, Vol 130, 363-372, 27 July 2007
Resource
A Tunable Genetic Switch Based on RNAi and Repressor Proteins for Regulating Gene Expression in Mammalian Cells

Tara L. Deans,1 Charles R. Cantor,1 and James J. Collins1,
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