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Posts Tagged ‘Synthetic Biology’

The dummy’s guide to engineering genes

In Uncategorized on February 9, 2008 at 10:57 pm

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New Bionanoscience dept launched at TU Delft Netherlands

In nano on February 9, 2008 at 10:54 pm

Over the next decade, TU Delft will invest €10m derived from its assets in the new department, which will form part of the university’s Kavli Institute of Nanoscience. The Kavli Foundation will also donate $5m (€3.4m).
The new department will explore the full spectrum from nanoscience to cell biology to synthetic biology to create gene regulation systems, artificial biomolecules and nanoparticles that can be deployed within the cell.

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Pursuing Synthetic Life, Dazzled by Reality NY Times

In Uncategorized on February 9, 2008 at 10:49 pm

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Solazyme is a synthetic biology company that unleashes the power of marine microbes to create clean and scalable solutions for the renewable energy, industrial chemical, and specialty ingredient markets.

In Uncategorized on February 9, 2008 at 10:48 pm

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U.K.’s Parliamentary Office of Science and Technology (POST) note on synthetic biology

In Uncategorized on February 9, 2008 at 10:43 pm

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[Synthetic Biology] Bottom-up genome assembly using the Bacillus subtilis genome vector

In Uncategorized on December 12, 2007 at 4:06 am

Japanese group assembles a 134.5 kb rice chloroplast genome from 4-6kb
pieces…

Abstract:
We established a protocol to construct complete recombinant genomes
from their small contiguous DNA pieces and obtained the genomes of
mouse mitochondrion and rice chloroplast using a B. subtilis genome
(BGM) vector. This method allows the design of any recombinant
genomes, valuable not only for fundamental research in systems biology
and synthetic biology but also for various applications in the life
sciences.

http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=18066072&itool=pubmed_DocSum

Extreme Monopoly: Venter’s Team Makes Vast Patent Grab on Synthetic Genomes

In Uncategorized on December 9, 2007 at 4:09 am

here

IGEM International Genetically Engineered Machine Competition 2007

In Uncategorized on November 6, 2007 at 2:28 am

The Winner of this year IGEM (more on IGEM International Genetically Engineered Machine Competition here

Winner Peking University
Towards Self-differentiated Bacterial Assembly Line
Our projects concern with the ability for bacterial cells to differentiate out of homogeneous conditions into populations with the division of labor. We aim at devices conferring host cells with the ability to form cooperating groups spontaneously and to take consecutive steps sequentially even when the genetic background and environmental inputs are identical. To break the mirror in such homogeneous condition, we need two devices respectively responsible for temporal and spatial differentiation. The implementation and application of such devices will lead to bioengineering where complex programs consisted of sequential steps (structure oriented programs) and cooperating agencies (forked instances of a single class, object and event oriented) can be embedded in a single genome. Although this “differentiation” process resemble the development of multicellular organism, we tend to use a more bioengineering style analogy: assembly line. Or maybe after some years from now, this will not be just an analogy.

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second place see some pressrelease here

A biological sensor that catches infections on hospital catheters at an early stage has been developed by Biochemistry and Bioengineering students and researchers at Imperial College London. moresee here

The other projects here

Synthetic biology governance; the newest

In Uncategorized on October 19, 2007 at 2:01 am

1) Synthetic Genomics: Options for Governance see here
The authors are mostly from the synbio field Michele S. Garfinkel, The J. Craig Venter Institute, Rockville, Maryland, Drew Endy, Massachusetts Institute of Technology, Cambridge, Massachusetts, Gerald L. Epstein, Center for Strategic and International Studies, Washington, District of Columbia and Robert M. Friedman, The J. Craig Venter Institute, Rockville, Maryland

2) The NGO response Syns of Omission: Civil Society Organizations Respond to Report on Synthetic Biology Governance from the J. Craig Venter Institute and Alfred P. Sloan Foundation see here

Scientists Synthesize Memory in Yeast Cells

In Uncategorized on September 15, 2007 at 12:57 am

FINDINGS:
Researchers in the Harvard Medical School Department of Systems Biology have constructed a memory loop out of bits of DNA. After being placed in a yeast cell, the loop continued throughout many cell divisions.
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Scientists a step nearer to creating artificial life

In Uncategorized on September 7, 2007 at 2:53 am

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New institute fuses science and engineering with medical research

In Uncategorized on September 7, 2007 at 1:41 am

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includes a synbio group

Microbial Fuel Cells

In nano on August 10, 2007 at 7:39 pm

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European Conference on Synthetic Biology (ECSB):

In Uncategorized on August 9, 2007 at 12:36 am

Design, Programming and Optimisation of Biological Systems
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Newest column of mine NBICS, Cultural Identity and Diversity, and the CBD

In Disabled People, nano on August 5, 2007 at 4:31 pm

NBICS, Cultural Identity and Diversity, and the CBD
this is the second part on the convention on biological diversity CBD
first one is
here

and all my columns are listed here

New recipe for sustainability: stem-cell burgers

In Stem Cell on August 3, 2007 at 10:46 pm

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Making Gasoline from Bacteria

In Uncategorized on August 1, 2007 at 3:05 pm

from here and more here
The biofuel of the future could well be gasoline. That’s the hope of one biotech startup that on Monday described for the first time how it is coaxing bacteria into producing hydrocarbons that could be processed into fuels like those made from petroleum.

LS9, a company based in San Carlos, CA, and founded by geneticist George Church, of Harvard Medical School, and plant biologist Chris Somerville, of Stanford University, had previously said that it was working on what it calls “renewable petroleum.” But at a Society for Industrial Microbiology conference on Monday, the company began speaking more openly about what it has accomplished: it has genetically engineered various bacteria, including E. coli, to custom-produce hydrocarbon chains.

New molecular switch for genes

In Uncategorized on July 31, 2007 at 1:03 pm

Researchers have created a molecular switch that can reversibly turn any mammalian gene on or off and control its level of expression. The results, published this week in Cell, provide a new level of precision in studying genes involved in biological processes and diseases, the authors say.
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Copyright © 2007 Cell Press. All rights reserved.
Cell, Vol 130, 363-372, 27 July 2007
Resource
A Tunable Genetic Switch Based on RNAi and Repressor Proteins for Regulating Gene Expression in Mammalian Cells

Tara L. Deans,1 Charles R. Cantor,1 and James J. Collins1,
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synthetic biology 3.0

In Uncategorized on July 13, 2007 at 5:44 pm

my new column is out
see here
older columns here

Countdown to a synthetic lifeform

In nano on July 13, 2007 at 3:00 pm

According to George Church at Harvard Medical School in Boston, who has devised a complete blueprint for a synthetic cell, an investment of around $10 million would be enough to turn the “bottom-up” dream into reality. “Our approach doesn’t require any super new technology,” he says.
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