Archive for the ‘Synthetic Biology’ Category
“Through incorporating principles of engineering, we’ve developed a language that can describe biology in the same way a biologist would,” says Gunawardena. “The potential here is enormous. This opens the door to actually performing discovery science, to look at things like drug interactions, right on the computer.”
Scientists in Germany have brought the prospect of generating cheap electricity from hydrogen a step closer by taking a snapshot of an elusive enzyme that can split the gas as efficiently as a platinum catalyst.
We describe a new class of DNA-like oligomers made exclusively of nonnatural, stable C-nucleosides. The nucleosides comprise four types of nonnatural bases attached to a deoxyribose through an acetylene bond with the β-configuration. The artificial DNA forms right-handed duplexes and triplexes with the complementary artificial DNA. The hybridization occurs spontaneously and sequence-selectively, and the resulting duplexes have thermal stabilities very close to those of natural duplexes. The artificial DNA might be applied to a future extracellular genetic system with information storage and amplifiable abilities.